Quantity | = | Concentration | x | Volume | x | Molecular Weight |
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AOB2076
CAS No:259793-96-9
Chemical Name: T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide; 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide
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Molecular Formula | C5H4FN3O2 |
Molecular Weight | 157.10 |
CAS Numbers | 259793-96-9 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | T-705 |
IUPAC/Chemical Name | 6-fluoro-3-hydroxy-2-pyrazinecarboxamide; 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide |
InChl Key | ZCGNOVWYSGBHAU-UHFFFAOYSA-N |
InChl Code | InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11) |
SMILES Code | FC1=CNC(C(C(N)=O)=N1)=O |
References | 1) Furuta, Y., Takahashi, K., Fukuda, Y., et al. In vitro and in vivo activities of anti-influenza virus compound T-705. Antimicrob. Agents and Chemother. 46(4), 977-981 (2002).2) Furuta, Y., Takahashi, K., Shiraki, K., et al. T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 82(3), 95-102 (2009). |
Selective inhibitor of viral RNA-dependent RNA polymerase, active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses