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AOB31807
CAS: 11000-17-2
Chemical Name: Antidiuretic hormone (ADH); Arginine vasopressin (AVP); Argipressin; CYFQNCPRG; H-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Arg-Gly-NH2
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $9.45 | Total: $945.00 |
1 | 50 | $10.92 | Total: $546.00 |
1 | 25 | $12.81 | Total: $320.25 |
1 | 10 | $15.12 | Total: $151.20 |
1 | 5 | $17.85 | Total: $89.25 |
Molecular Formula | C46H65N15O12S2 |
Molecular Weight | 1084.24 |
CAS Numbers | 11000-17-2 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | Vasopressin; antidiuretic hormone (ADH); arginine vasopressin (AVP) ; argipressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide Bridge Cys1-Cys6) |
IUPAC/Chemical Name | (S)-N-((S)-1-((2-amino-2-oxoethyl)amino)-5-guanidino-1-oxopentan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide |
InChl Key | KBZOIRJILGZLEJ-LGYYRGKSSA-N |
InChl Code | InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1 |
SMILES Code | O=C([C@@H](N)CSSC[C@H](NC1=O)C(N2[C@H](C(N[C@H](C(NCC(N)=O)=O)CCCNC(N)=N)=O)CCC2)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC(N)=O)=O)CCC(N)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4 |
References | 1) Gizowski C, Trudel E, Bourque CW. Central and peripheral roles of vasopressin in the circadian defense of body hydration. Best Pract Res Clin Endocrinol Metab. 2017 Dec;31(6):535-546. doi: 10.1016/j.beem.2017.11.001. Epub 2017 Nov 13. Review. PubMed PMID: 29224666. 2) Terranova JI, Ferris CF, Albers HE. Sex Differences in the Regulation of Offensive Aggression and Dominance by Arginine-Vasopressin. Front Endocrinol (Lausanne). 2017 Nov 14;8:308. doi: 10.3389/fendo.2017.00308. eCollection 2017. Review. PubMed PMID: 29184535; PubMed Central PMCID: PMC5694440. |
Peptide prohormone, increasing the amount of solute-free water reabsorbed back into the circulation from the filtrate in the kidney tubules of the nephrons, constricting arterioles to increase peripheral vascular resistance and raise arterial blood pressure, playing an important role in social behavior, sexual motivation and pair bonding, and maternal responses to stress