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EF5
AOBS1961
CAS No: 152721-37-4
Chemical Name: 2-
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.28 | Total: $1,327.50 |
| 1 | 50 | $15.34 | Total: $767.00 |
| 1 | 25 | $18.00 | Total: $449.88 |
| 1 | 10 | $21.24 | Total: $212.40 |
| 1 | 5 | $25.08 | Total: $125.38 |
Data sheet
| Molecular Formula | C8H7F5N4O3 |
| Molecular Weight | 302.16 |
| CAS Numbers | 152721-37-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSA: 10 mg/mL |
| Purity | 98% by HPLC |
More info
A 2-nitroimidazole-based hypoxia marker corresponding to a pentafluorinated derivative of the hypoxic cell-radiation sensitizer etanidazole. Under low oxygen (hypoxic) condition, reductive activation of its 2-nitroimidazole moiety leads to enhanced EF5 adduct formation with protein thiols and reduced glutathione. The pentafluorination derivatization substantially decreases the proportion of low molecular weight hydrolytic fragmentation of the adducts, making EF5 superior to etanidazole when utilized as a hypoxia marker by immunohistological staining.