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> G Protein-Coupled Receptor Ligands>Prostanoid Receptors> SW033291 Bulk

Prostanoid Receptors

SW033291 View larger

SW033291 Bulk

AOB5231

CAS No: 459147-39-8

 

Chemical Name:2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine

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Data sheet

Molecular FormulaC21H20N2OS3
Molecular Weight412.59
CAS Numbers459147-39-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymSW033291; SW 033291; SW 033291.
IUPAC/Chemical Name2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
InChl KeyLCYAYKSMOVLVRL-UHFFFAOYSA-N
InChl CodeInChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
SMILES CodeNC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21
References1) Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD. TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340. PubMed PMID: 26068857; PubMed Central PMCID: PMC4481126.

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Novel inhibitor of 15-prostaglandin dehydrogenase (15-PGDH), triggering tissue regeneration and healing of damaged tissues