Prostanoid Receptors

BI-671800 View larger

BI-671800

AT14565

CAS 1093108-50-9

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$76.00

$76.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $34.20 Total: $3,420.00
150 $39.52 Total: $1,976.00
125 $46.36 Total: $1,159.00
110 $54.72 Total: $547.20
15 $64.60 Total: $323.00

Data sheet

Molecular FormulaC25H26F3N5O3
Molecular Weight501.5
CAS Numbers1093108-50-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCN(C)c1nc(Cc2ccc(NC(=O)c3ccc(cc3)C(F)(F)F)cc2)nc(N(C)C)c1CC(O)=O
ReferencesBoehme SA, et al. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. Int Immunol. 2009 Jan;21[1] 81-93.

More info

BI-671800 (AP-761) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2CRTH2). With IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has the potential to treat poorly controlled asthma[2].