Prostanoid Receptors

Tebufelone View larger

Tebufelone

AT68155

CAS 112018-00-5

More details

Molarity Calculation Cart®

HOW TO ORDER

$44.00

$44.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.80 Total: $1,980.00
150 $22.88 Total: $1,144.00
125 $26.84 Total: $671.00
110 $31.68 Total: $316.80
15 $37.40 Total: $187.00

Data sheet

Molecular FormulaC20H28O2
Molecular Weight300.44
CAS Numbers112018-00-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC1=C(C(C)(C)C)C=C(C(CCCC#C)=O)C=C1C(C)(C)C
ReferencesPowell JH, et al. Antipyretic activity of tebufelone [NE-11740] in man. Agents Actions Suppl. 1991 ; 32 45-49.

More info

Tebufelone is a potent in vitro inhibitor of CO , a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has shown potent anti-inflammatory, analgesic and anti-reticulitis properties in various animal models. Tebufelone potently inhibits the formation of prostaglandins (PGE2) and blocks the formation of lipoxygenase pathway products [leukotriene (LTB4)] in rat macrophages (IC50 = 20 microM) and human whole blood (IC50 = 22 microM) in vitro. = 20 microM) and human whole blood (IC50 = 22 microM) from the formation of lipoxygenase pathway products [leukotriene (LTB4)] in vitro.