Protease

Marizomib View larger

Marizomib

AT16012

CAS 437742-34-2

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$470.00

$470.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $211.50 Total: $21,150.00
150 $244.40 Total: $12,220.00
125 $286.70 Total: $7,167.50
110 $338.40 Total: $3,384.00
15 $399.50 Total: $1,997.50

Data sheet

Molecular FormulaC15H20ClNO4
Molecular Weight313.78
CAS Numbers437742-34-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[C@@H](O)([C@]12[C@](C)([C@@H](CCCl)C(=O)N1)OC2=O)[C@]3(CCCC=C3)[H]
ReferencesDi K, et al. Marizomib activity as a single agent in malignant gliomas ability to cross the blood-brainbarrier. Neuro Oncol. 2016 Jun;18[6] 840-8.

More info

Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (?5), CT-T-laspase-like (C-L, ?1), and trypsin-like (T-L, ?2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectively.