Protease

MG-115 View larger

MG-115

AT21617

CAS 133407-86-0

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$82.00

$82.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.90 Total: $3,690.00
150 $42.64 Total: $2,132.00
125 $50.02 Total: $1,250.50
110 $59.04 Total: $590.40
15 $69.70 Total: $348.50

Data sheet

Molecular FormulaC25H39N3O5
Molecular Weight461.59
CAS Numbers133407-86-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C=O
ReferencesRock KL, et, al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 1994 Sep 9;78[5] 761-71.

More info

MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis [1] [2] [3].