Protease

FSLLRY-NH2 TFA(245329-02-6 free base) View larger

FSLLRY-NH2 TFA(245329-02-6 free base)

ATP1904L

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$83.00

$83.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $37.35 Total: $3,735.00
150 $43.16 Total: $2,158.00
125 $50.63 Total: $1,265.75
110 $59.76 Total: $597.60
15 $70.55 Total: $352.75

Data sheet

Molecular FormulaC41H61F3N10O10
Molecular Weight910.99
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=CC=C2)N.O=C(O)C(F)(F)F
ReferencesMcLarty et al [2011] Tryptaseprotease-activated receptor 2 interactions induce selective mitogen-activated protein kinase signaling and collagen synthesis by cardiac fibroblasts. Hypertension 58 264 PMID

More info

FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.