Protein Control Ligand

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SAFit1

AOB6549

CAS No: 1643125-32-9

 

Chemical Name: 2-(3-((R)-1-((S)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid

 

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$53.00

$53.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $23.85 Total: $2,385.00
50 $27.56 Total: $1,378.00
25 $32.33 Total: $808.25
10 $38.16 Total: $381.60
5 $45.05 Total: $225.25

Data sheet

Molecular FormulaC42H53NO11
Molecular Weight747.87
CAS Numbers1643125-32-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymSAFit1; SA-Fit-1; SAF-it-1; SAF it 1; SA Fit 1
IUPAC/Chemical Name2-(3-((R)-1-((S)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid
InChl KeyOEQZPFWOEOOISR-AKTKKGGCSA-N
InChl CodeInChI=1S/C42H53NO11/c1-48-34-20-18-27(22-35(34)49-2)17-19-33(29-14-11-15-31(23-29)53-26-38(44)45)54-42(47)32-16-9-10-21-43(32)41(46)39(28-12-7-6-8-13-28)30-24-36(50-3)40(52-5)37(25-30)51-4/h11,14-15,18,20,22-25,28,32-33,39H,6-10,12-13,16-17,19,21,26H2,1-5H3,(H,44,45)/t32-,33+,39-/m0/s1
SMILES CodeO=C(O)COC1=CC=CC([C@H](OC([C@H]2N(C([C@@H](C3CCCCC3)C4=CC(OC)=C(OC)C(OC)=C4)=O)CCCC2)=O)CCC5=CC=C(OC)C(OC)=C5)=C1
ReferencesGaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, Schmidt MV, Touma C, Bracher A, Hausch F. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nat Chem Biol. 2015 Jan;11(1):33-7

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Highly selective inhibitor of the ​FK506-binding protein 51 (FKBP51)

 

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