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> Pathway Inhibitors>Protein Inhibitors>C25-140

Protein Inhibitors

C25-140 View larger

C25-140

AOB36355

CAS No: 1358099-18-9

 

Chemical Name: 1-(4-Benzylpiperidin-1-yl)-3-(3,5-dimethyl-1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl)propan-1-one

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$31.00

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $26.35 Total: $131.75
110 $22.32 Total: $223.20
125 $18.91 Total: $472.75
150 $16.12 Total: $806.00
1100 $13.95 Total: $1,395.00

Data sheet

Molecular FormulaC26H31N7O
Molecular Weight457.58
CAS Numbers1358099-18-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymC25140; C-25140; C 25140; C25 140; C25-140; C-25-140
IUPAC/Chemical Name1-(4-Benzylpiperidin-1-yl)-3-(3,5-dimethyl-1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl)propan-1-one
InChl KeyHFKVRXVHZGBRKF-UHFFFAOYSA-N
InChl CodeInChI=1S/C26H31N7O/c1-18-23(19(2)32(29-18)25-11-10-24-28-27-20(3)33(24)30-25)9-12-26(34)31-15-13-22(14-16-31)17-21-7-5-4-6-8-21/h4-8,10-11,22H,9,12-17H2,1-3H3
SMILES CodeO=C(N1CCC(CC2=CC=CC=C2)CC1)CCC3=C(C)N(C4=NN5C(C=C4)=NN=C5C)N=C3C
PubChem IDBrenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity. J Biol Chem. 2018 Aug 24;293(34):13191-13203.

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The first-in-class protein-protein-interaction inhibitor of a RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) binding