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View larger DRAinh-A250
AOB36412
CAS: 858747-13-4
Chemical Name: 2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Data sheet
| Molecular Formula | C20H17BrO5 |
| Molecular Weight | 417.26 |
| CAS Numbers | 858747-13-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| Synonym | DRAinhA250; DRAinh A250; DRAinh-A250 |
| IUPAC/Chemical Name | 2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid |
| InChl Key | STHJGDCGBDTTHP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H17BrO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23) |
| SMILES Code | O=C(O)CC(C1=O)=C(C)C2=C(O1)C(C)=C(OCC3=CC=CC(Br)=C3)C=C2 |
| References | 1) Haggie PM, Cil O, Lee S, Tan JA, Rivera AA, Phuan PW, Verkman AS. SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation. JCI Insight. 2018 Jul 26;3(14). pii: 121370. doi: 10.1172/jci.insight.121370. [Epub ahead of print] PubMed PMID: 30046015; PubMed Central PMCID: PMC6124422. |
More info
Novel SLC26A3 inhibitor, blocking colonic fluid absorption and reducing constipation