Protein Inhibitors

DRAinh-A250 View larger

DRAinh-A250

AOB36412

CAS: 858747-13-4

Chemical Name: 2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid

More details

Molarity Calculation Cart®

HOW TO ORDER

$129.00

$129.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $58.05 Total: $5,805.00
50 $67.08 Total: $3,354.00
25 $78.69 Total: $1,967.25
10 $92.88 Total: $928.80
5 $109.65 Total: $548.25

Data sheet

Molecular FormulaC20H17BrO5
Molecular Weight417.26
CAS Numbers858747-13-4
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
SynonymDRAinhA250; DRAinh A250; DRAinh-A250
IUPAC/Chemical Name2-(7-((3-Bromobenzyl)oxy)-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid
InChl KeySTHJGDCGBDTTHP-UHFFFAOYSA-N
InChl CodeInChI=1S/C20H17BrO5/c1-11-15-6-7-17(25-10-13-4-3-5-14(21)8-13)12(2)19(15)26-20(24)16(11)9-18(22)23/h3-8H,9-10H2,1-2H3,(H,22,23)
SMILES CodeO=C(O)CC(C1=O)=C(C)C2=C(O1)C(C)=C(OCC3=CC=CC(Br)=C3)C=C2
References1) Haggie PM, Cil O, Lee S, Tan JA, Rivera AA, Phuan PW, Verkman AS. SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation. JCI Insight. 2018 Jul 26;3(14). pii: 121370. doi: 10.1172/jci.insight.121370. [Epub ahead of print] PubMed PMID: 30046015; PubMed Central PMCID: PMC6124422.

More info

Novel SLC26A3 inhibitor, blocking colonic fluid absorption and reducing constipation