Protein Inhibitors

BC-1471 View larger

BC-1471

AOB36470

CAS: 896683-78-6

 

Chemical Name: N-(Furan-2-ylmethyl)-2-((6-morpholino-4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-yl)thio)acetamide

AOBIOUS launched this product in 2020

CITATIONS - Publications That Use AOBIOUS Product

1) Neoplasia. 2021 Jun; 23(6): 607–623

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HOW TO ORDER

$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC27H28N4O4S
Molecular Weight504.61
CAS Numbers896683-78-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBC1471, BC 1471
IUPAC/Chemical NameN-(Furan-2-ylmethyl)-2-((6-morpholino-4-oxo-3-phenethyl-3,4-dihydroquinazolin-2-yl)thio)acetamide
InChl KeyGJKRCJKXXVVAMV-JOCHJYFZSA-N
InChl CodeInChI=1S/C27H32N4O4S/c32-25(28-18-22-7-4-14-35-22)19-36-27-29-24-9-8-21(30-12-15-34-16-13-30)17-23(24)26(33)31(27)11-10-20-5-2-1-3-6-20/h1-3,5-6,8-9,17,22H,4,7,10-16,18-19H2,(H,28,32)/t22-/m1/s1
SMILES CodeO=C(NC[C@@H]1OCCC1)CSC(N2CCC3=CC=CC=C3)=NC4=C(C=C(N5CCOCC5)C=C4)C2=O
References1) JS Bednash et al., Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity, Nat Commun. 2017; 8: 15203.

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Novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism

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