Array
(
)
1
> Pathway Inhibitors>Protein Inhibitors>ML036

Protein Inhibitors

ML036 View larger

ML036

AOB1150

CAS: 1014405-03-8

 

Chemical Name: tert-Butyl N-[(2S)-1-[2-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]-carbonylhydrazinyl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate 

More details

1000 Items

Molarity Calculation Cart®

HOW TO ORDER

$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $41.65 Total: $208.25
110 $35.28 Total: $352.80
125 $29.89 Total: $747.25
150 $25.48 Total: $1,274.00
1100 $22.05 Total: $2,205.00

Data sheet

Molecular FormulaC28H33N5O6
Molecular Weight535.60
CAS Numbers1014405-03-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
SynonymOxocarbazate; CID 23631927; CID23631927; CID-23631927;
IUPAC/Chemical NameN-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan 2-[[2-(3,4-dihydro-1(2H)-quinolinyl)-2-oxoethoxy]carbonyl]hydrazide
InChl KeyMITOFRSPGLYHSJ-QFIPXVFZSA-N
InChl CodeInChI=1S/C28H33N5O6/c1-28(2,3)39-26(36)30-22(15-19-16-29-21-12-6-5-11-20(19)21)25(35)31-32-27(37)38-17-24(34)33-14-8-10-18-9-4-7-13-23(18)33/h4-7,9,11-13,16,22,29H,8,10,14-15,17H2,1-3H3,(H,30,36)(H,31,35)(H,32,37)/t22-/m0/s1
SMILES CodeO=C(NNC(OCC(N1CCCC2=C1C=CC=C2)=O)=O)[C@@H](NC(OC(C)(C)C)=O)CC3=CNC4=C3C=CC=C4
References1) Shah PP, Wang T, Kaletsky RL, Myers MC, Purvis JE, Jing H, Huryn DM, Greenbaum DC, Smith AB 3rd, Bates P, Diamond SL. A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. Mol Pharmacol. 2010 Aug;78(2):319-24. doi: 10.1124/mol.110.064261. Epub 2010 May 13. PubMed PMID: 20466822; PubMed Central PMCID: PMC2917856.

More info

Novel potent inhibitor of human cathepsin L