Protein Inhibitors

SB-715992 View larger

SB-715992

AOB87364

CAS No:336113-53-2

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC30H33ClN4O2
Molecular Weight517.06
CAS Numbers336113-53-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC

More info

The first potent, highly specific small-molecule inhibitor of the human kinesin spindle protein (KSP or KIF11 or Eg5), that induces mitosis-phase (M-phase) arrest followed by apoptosis in either the M-phase (via mitotic catastrophe) or G1-phase of the cell-cycle. Ispinesib alters the ability of KSP to bind to microtubules and inhibits its movement by preventing the release of ADP without preventing the release of the KSP−ADP complex from the microtubule