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Palomid 529
AOB4380
CAS No: 914913-88-5
Chemical Name: P529; 8-(1-hydroxyethyl)-2-methoxy-3-((4-methoxybenzyl)oxy)-6H-benzo[c]chromen-6-one
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $5.85 | Total: $585.00 |
| 1 | 50 | $6.76 | Total: $338.00 |
| 1 | 25 | $7.93 | Total: $198.25 |
| 1 | 10 | $9.36 | Total: $93.60 |
| 1 | 5 | $11.05 | Total: $55.25 |
Data sheet
| Molecular Formula | C24H22O6 |
| Molecular Weight | 406.43 |
| CAS Numbers | 914913-88-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Palomid 529; Palomid-529; Palomid529; P529; P 529; P-529.IUPAC/Chemical Name:InChi Key:InChi Code:SMILES Code: |
| IUPAC/Chemical Name | 8-(1-hydroxyethyl)-2-methoxy-3-((4-methoxybenzyl)oxy)-6H-benzo[c]chromen-6-one |
| InChl Key | YEAHTLOYHVWAKW-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H22O6/c1-14(25)16-6-9-18-19-11-22(28-3)23(12-21(19)30-24(26)20(18)10-16)29-13-15-4-7-17(27-2)8-5-15/h4-12,14,25H,13H2,1-3H3 |
| SMILES Code | O=C1C2=CC(C(O)C)=CC=C2C3=C(O1)C=C(OCC4=CC=C(OC)C=C4)C(OC)=C3 |
| References | 1) He TY, Tsai LH, Huang CC, Chou MC, Lee H. LKB1 Loss at Transcriptional Level Promotes Tumor Malignancy and Poor Patient Outcomes in Colorectal Cancer. Ann Surg Oncol. 2014 May 31. [Epub ahead of print] PubMed PMID: 24879590. 2) Gravina GL, Marampon F, Sherris D, Vittorini F, Di Cesare E, Tombolini V, Lenzi A, Jannini EA, Festuccia C. Torc1/Torc2 inhibitor, Palomid 529, enhances radiation response modulating CRM1-mediated survivin function and delaying DNA repair in prostate cancer models. Prostate. 2014 Jun;74(8):852-68. doi: 10.1002/pros.22804. Epub 2014 Apr 8. PubMed PMID: 24715588. |
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Novel PI3K/Akt/mTOR inhibitor, reducing tumor growth, tumor angiogenesis, and vascular permeability