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View larger Sabizabulin
AT17228
CAS 1332881-26-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.10 | Total: $535.50 |
| 1 | 10 | $90.72 | Total: $907.20 |
| 1 | 25 | $76.86 | Total: $1,921.50 |
| 1 | 50 | $65.52 | Total: $3,276.00 |
| 1 | 100 | $56.70 | Total: $5,670.00 |
Data sheet
| Molecular Formula | C21H19N3O4 |
| Molecular Weight | 377.39 |
| CAS Numbers | 1332881-26-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(cc(OC)c1OC)C(=O)c1c[nH]c(n1)-c1c[nH]c2ccccc12 |
| References | Wang Q, et al. Structure-Guided Design, Synthesis, and Biological Evaluation of [2-[1H-Indol-3-yl]-1H-imidazol-4-yl][3,4,5-trimethoxyphenyl] Methanone [ABI-231] Analogues Targeting the Colchicine Binding Site in Tubulin. J Med Chem. 2019 Jul 12. |
More info
Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of ? and ? tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervical cancer cells via targeting HPV E6 and E7. Sabizabulin shows antiproliferative activity and can be used in prostate cancer studies.