Protein Inhibitors

Lexibulin View larger

Lexibulin

AT2090

CAS 917111-44-5

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC24H30N6O2
Molecular Weight434.53
CAS Numbers917111-44-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCC[C@H](Nc1nc(ncc1C)-c1ccc(NC(=O)NCC)c(OC)c1)c1cccnc1
ReferencesBurns CJ, et al. Mol Cancer Ther, 2009, 8[11], 3036-3045.

More info

Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2M phase; this may result in disruption of the tumor vasculature and tumor blood flow, and tumor cell death.