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Protein Inhibitors
- Protein Control Ligand
- Pathway Inhibitors
- Enzyme Inhibitors
- Kinase Inhibitors
- Protease
- Synthase
- p18
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- p70
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- Hydroxylases
- Ubiquitin-Activating Enzyme
- Adenosine Deaminase
- Clathrin
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- p68
- ACE
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- DHFR
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- Reductase
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- Topoisomerase
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- Protein Inhibitors
- Transporter Inhibitors
- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
- AChE
- Peptidase
- Autophagy
- Toll-Like Receptor (TLR)
- Enzyme Inhibitors
- Function Modulators
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- G Protein-Coupled Receptor Ligands
- 5HT Receptors
- Adrenoceptor
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- Cannabinoid Receptors
- CCK Receptors
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- Ghrelin Receptors
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- Motilin Receptors
- Muscarinic Receptor
- Neuropeptide Receptors
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- Ryanodine receptor
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- Imidazoline receptor
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- Biomarkers and Buffer Solutions
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $129.20 | Total: $646.00 |
| 1 | 10 | $109.44 | Total: $1,094.40 |
| 1 | 25 | $92.72 | Total: $2,318.00 |
| 1 | 50 | $79.04 | Total: $3,952.00 |
| 1 | 100 | $68.40 | Total: $6,840.00 |
Data sheet
| Molecular Formula | C17H17F3N6O2 |
| Molecular Weight | 394.35 |
| CAS Numbers | 75689-93-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1(C)CN(C(=O)N1)c1ncc(C(=O)Nc2cccc(c2)C(F)(F)F)c(N)n1 |
| References | Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63[9] 1755-61. |
More info
Imanixil (HOE-402 free base) is an LDL receptor (LDLR) inducer, a hypolipidemic and hypocholesterolemic compound with antiatherogenic activity that inhibits the production of very low-density lipoproteins (VLDLs).Imanixil acts by stimulating the LDL receptor pathway.