Protein Inhibitors

McMMAF View larger

McMMAF

AT16031

CAS 863971-19-1

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC49H76N6O11
Molecular Weight925.16
CAS Numbers863971-19-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(CCCCCN3C(=O)C=CC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
ReferencesPolson AG, et al. Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma target and linker-drug selection. Cancer Res. 2009 Mar 15;69[6] 2358-2364.

More info

McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.