Protein Inhibitors

Mavacamten View larger

Mavacamten

AT7134

CAS 1642288-47-8

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$34.00

$34.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.30 Total: $1,530.00
150 $17.68 Total: $884.00
125 $20.74 Total: $518.50
110 $24.48 Total: $244.80
15 $28.90 Total: $144.50

Data sheet

Molecular FormulaC15H19N3O2
Molecular Weight273.33
CAS Numbers1642288-47-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O
ReferencesKawas R F , Anderson R L , Ingle S R B , et al. A small molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle[J]. Journal of Biological Chemistry, 2017, 292[40] jbc.M117.776815.

More info

Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)