Protein Inhibitors

Suprafenacine View larger

Suprafenacine

AT28886

CAS 1477482-50-0

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$82.00

$82.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $36.90 Total: $3,690.00
150 $42.64 Total: $2,132.00
125 $50.02 Total: $1,250.50
110 $59.04 Total: $590.40
15 $69.70 Total: $348.50

Data sheet

Molecular FormulaC16H18N4O
Molecular Weight282.34
CAS Numbers1477482-50-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC1=CC=C(C=NNC(=O)C2=NNC3=C2CCCC3)C=C1
ReferencesChoi BH, Chattopadhaya S, Thanh le N, Feng L, Nguyen QT, Lim CB, Harikishore A, Nanga RP, Bharatham N, Zhao Y, Liu X, Yoon HS. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS One. 2014 Oct 29;9[10] e110955.

More info

Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.