Protein Inhibitors

Rotigaptide TFA(355151-12-1 free base) View larger

Rotigaptide TFA(355151-12-1 free base)

AT16790L

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$115.00

$115.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $51.75 Total: $5,175.00
150 $59.80 Total: $2,990.00
125 $70.15 Total: $1,753.75
110 $82.80 Total: $828.00
15 $97.75 Total: $488.75

Data sheet

Molecular FormulaC30H40F3N7O11
Molecular Weight731.67
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@H](C(=O)NCC(=O)N)NC(=O)CNC(=O)[C@H]1C[C@@H](CN1C(=O)[C@H]2CCCN2C(=O)[C@@H](CC3=CC=C(C=C3)O)NC(=O)C)O.OC(C(F)(F)F)=O
ReferencesGhiasi SM, Hansen JB, Christensen DP, Tyrberg B, Mandrup-Poulsen T. The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets. Int J Mol Sci. 2020;21[12] 4311. Published 2020 Jun 17. doi 10.3390ijms21124311

More info

Rotigaptide TFA(355151-12-1 free base) is a novel and specific modulator of Cx43 and is a potent AAP. Rotigaptide TFA(355151-12-1 free base) prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress.