Protein Inhibitors

CK-666 View larger

CK-666

AT10826

CAS 442633-00-3

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.05 Total: $1,305.00
150 $15.08 Total: $754.00
125 $17.69 Total: $442.25
110 $20.88 Total: $208.80
15 $24.65 Total: $123.25

Data sheet

Molecular FormulaC18H17FN2O
Molecular Weight296.34
CAS Numbers442633-00-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1[nH]c2ccccc2c1CCNC(=O)c1ccccc1F
ReferencesHetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 23 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20[5] 701-12.

More info

CK-666 is a cell-permeable inhibitor of the actin-related protein Arp23 complex, binding to and stabilizing its inactive state, thereby preventing the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) configuration.