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View larger Tubulin polymerization-IN-47
AT77651
CAS 2834087-62-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $20.70 | Total: $2,070.00 |
| 1 | 50 | $23.92 | Total: $1,196.00 |
| 1 | 25 | $28.06 | Total: $701.50 |
| 1 | 10 | $33.12 | Total: $331.20 |
| 1 | 5 | $39.10 | Total: $195.50 |
Data sheet
| Molecular Formula | C22H21N3O3 |
| Molecular Weight | 375.42 |
| CAS Numbers | 2834087-62-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C)C=1C=C(C=2C=3N(C=C(N3)C4=CC=C(C)C=C4)C=CN2)C=C(OC)C1OC |
| References | Joshua Thammathong, et al. Fused Imidazopyrazine-Based Tubulin Polymerization Inhibitors Inhibit Neuroblastoma Cell Function. ACS Med. Chem. Lett. 2023. |
More info
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell lines, respectively. Tubulin polymerization-IN-47 is a candidate compound for the treatment of hepatocellular carcinoma, colon cancer, lung cancer and breast cancer.