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Camlipixant (BLU-5937)
AOB17878
CAS 1621164-74-6
Chemical Name: Camlipixant; Methyl (S)-2-((2-(2,6-difluoro-4-(methylcarbamoyl)phenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)methyl)morpholine-4-carboxylate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $58.05 | Total: $5,805.00 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 5 | $109.65 | Total: $548.25 |
Data sheet
| Molecular Formula | C23H24F2N4O4 |
| Molecular Weight | 458.47 |
| CAS Numbers | 1621164-74-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Camlipixant; BLU5937; BLU 5937; BLU-5937 |
| IUPAC/Chemical Name | methyl (2S)-2-({2-[2,6-difluoro-4- (methylcarbamoyl)phenyl]-7-methylimidazo[1,2- a]pyridin-3-yl}methyl)morpholine-4-carboxylate |
| InChl Key | SEHLMRJSQFAPCJ-HNNXBMFYSA-N |
| InChl Code | InChI=1S/C23H24F2N4O4/c1-13-4-5-29-18(11-15-12-28(6-7-33-15)23(31)32-3)21(27-19(29)8-13)20-16(24)9-14(10-17(20)25)22(30)26-2/h4-5,8-10,15H,6-7,11-12H2,1-3H3,(H,26,30)/t15-/m0/s1 |
| SMILES Code | CC1=CC(N2C=C1)=NC(C3=C(F)C=C(C(NC)=O)C=C3F)=C2C[C@H]4CN(C(OC)=O)CCO4 |
| References | 1) Garceau D, Chauret N. BLU-5937: A selective P2X3 antagonist with potent anti-tussive effect and no taste alteration. Pulm Pharmacol Ther. 2019 Jun;56:56-62. 2) Marucci G, Dal Ben D, Buccioni M, Martí Navia A, Spinaci A, Volpini R, Lambertucci C. Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications. Expert Opin Ther Pat. 2019 Nov 20:1-21. doi: 10.1080/13543776.2019.1693542. [Epub ahead of print] PubMed PMID: 31726893. |
More info
Novel selective P2X3 antagonist with potent anti-tussive effect and no taste alteration