Purinergic Receptors

CPI-444 View larger

CPI-444

AT7183

CAS 1202402-40-1

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.05 Total: $1,305.00
150 $15.08 Total: $754.00
125 $17.69 Total: $442.25
110 $20.88 Total: $208.80
15 $24.65 Total: $123.25

Data sheet

Molecular FormulaC20H21N7O3
Molecular Weight407.43
CAS Numbers1202402-40-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc(o1)-c1nc(N)nc2n(Cc3cccc(CO[C@H]4CCOC4)n3)nnc12
ReferencesStephen Willingham, et al. Abstract PR04 CPI-444 A potent and selective inhibitor of A2AR induces antitumor responses alone and in combination with anti-PD-L1 in preclinical and clinical studies.Cancer Immunoly Research. September 25-28, 2016.

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CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2neu-expressing breast cancer.