Purinergic Receptors

Gefapixant View larger

Gefapixant

AT5099

CAS 1015787-98-0

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC14H19N5O4S
Molecular Weight353.4
CAS Numbers1015787-98-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(N)(=O)=O
ReferencesAnthony P. Ford, et al. The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders. Front Cell Neurosci. 2013; 7 267.

More info

Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X23 heterotrimeric receptors.