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View larger Sivopixant
AT40045
CAS 2414285-40-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.10 | Total: $535.50 |
| 1 | 10 | $90.72 | Total: $907.20 |
| 1 | 25 | $76.86 | Total: $1,921.50 |
| 1 | 50 | $65.52 | Total: $3,276.00 |
| 1 | 100 | $56.70 | Total: $5,670.00 |
Data sheet
| Molecular Formula | C25H22ClN5O5 |
| Molecular Weight | 507.93 |
| CAS Numbers | 2414285-40-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(N1C(=NC2=CC=C(OC3=CC=CC=N3)C=C2)NC(=O)N(C[C@@H](C(O)=O)C)C1=O)C4=CC=C(Cl)C=C4 |
| References | Kai H, et al. Discovery of clinical candidate Sivopixant [S-600918] Lead optimization of dioxotriazine derivatives as selective P2X3 receptor antagonists [published online ahead of print, 2021 Sep 26]. Bioorg Med Chem Lett. 2021;52 128384. |
More info
Sivopixant (S-600918) (S-600918) is a potent and selective antagonist of P2X3 receptor (P2X3 IC 50 =4.2 nM; P2X23 IC 50 =1100 nM). Sivopixant shows strong analgesic effect .