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View larger JNJ-42253432
AT27683
CAS 1428327-35-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.00 | Total: $425.00 |
| 1 | 10 | $72.00 | Total: $720.00 |
| 1 | 25 | $61.00 | Total: $1,525.00 |
| 1 | 50 | $52.00 | Total: $2,600.00 |
| 1 | 100 | $45.00 | Total: $4,500.00 |
Data sheet
| Molecular Formula | C28H38N4O |
| Molecular Weight | 446.63 |
| CAS Numbers | 1428327-35-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1CCc2c(C1)cccc2C(=O)NCC1(CCCCC1)N1CCN(CC1)c1ccccc1 |
| References | Brian Lord.et al.Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.J Pharmacol Exp Ther. 2014 Dec;351[3] 628-41. |
More info
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.