Purinergic Receptors

JNJ-55308942 View larger

JNJ-55308942

AT37806

CAS 2166558-11-6

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$60.00

$60.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $27.00 Total: $2,700.00
150 $31.20 Total: $1,560.00
125 $36.60 Total: $915.00
110 $43.20 Total: $432.00
15 $51.00 Total: $255.00

Data sheet

Molecular FormulaC17H12F5N7O
Molecular Weight425.32
CAS Numbers2166558-11-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@H]1Cc2c(CN1C(=O)c1ccnc(c1F)C(F)(F)F)nnn2-c1ncc(F)cn1
ReferencesBhattacharya A, et al. Neuropsychopharmacology of JNJ-55308942 evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia. Neuropsychopharmacology. 2018;43[13] 2586-2596.

More info

JNJ-55308942 is a selective and brain-penetrant antagonist of P2X7 functional with IC50s of 10 and 15 nM and Kis of 7.1 and 2.9 nM for hP2X7 and rP2X7, respectively.