Array
(
)
1
> G Protein-Coupled Receptor Ligands>Purinergic Receptors>IB-MECA (Piclidenoson)

Purinergic Receptors

IB-MECA View larger

IB-MECA (Piclidenoson)

AOB5361

CAS No:152918-18-8

Chemical Name: 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide

More details

475 Items

Molarity Calculation Cart®

HOW TO ORDER

$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $17.85 Total: $89.25
110 $15.12 Total: $151.20
125 $12.81 Total: $320.25
150 $10.92 Total: $546.00
1100 $9.45 Total: $945.00

Data sheet

Molecular FormulaC18H19IN6O4
Molecular Weight510.29
CAS Numbers152918-18-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilitySoluble to 25 mM in DMSO
Stock Solution Guide10 mMol/5.1 mg/1 mL of Solvent
Purity98% by HPLC
SynonymPiclidenoson; 3-IB-Meca
IUPAC/Chemical Name1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide
InChl KeyHUJXGQILHAUCCV-MOROJQBDSA-N
InChl CodeInChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1
SMILES CodeCNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)NCC4=CC(=CC=C4)I)O)O
References1) Shin Y, et al. Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors? Drug Dev Res. 1996 Sep 1;39(1):36-46.

2) Abedi H, et al. Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines. Tumour Biol. 2014 Nov;35(11):11027-11039.

More info

A potent and selective A3 adenosine receptor agonist