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DESCRIPTION | |
Species Reactivity | Human CRP |
Immunogen | Full length recombinant human CRP Protein |
Purity | > 95% determined by SDS-PAGE |
Formulation | 0.22 μM filtered solution of PBS, 0.09% NaN3, pH 7.4 |
Size | 50µl |
APPLICATION | |
ELISA | 1) capture antibody: rabbit anti CRP monoclonal antibody (clone 56D8, AP36773MD8) at 1 µg/ml 2) detection antibody: rabbit anti CRP monoclonal antibody (clone 57A6, AP36773MA6) at 0.5 µg/ml |
Pairing Antibody | AP36773MA6 |
Immunohistochemistry | |
Research Use or Further Manufacturing Only. | |
PREPARATION AND STORAGE | |
Preparation | Monoclonal antibody is produced by immunizing rabbit with full length human CRP and purified using protein A resin. |
Storage | This antibody is shipped at 4 oC. This product is stable for 12 months from date of receipt when stored at -20oC to -70oC. Avoid freeze/thaw cycles |
BACKGROUND
C-Reactive Protein (CRP) is an annular, pentameric protein found in blood plasma. CRP belongs to the ß-globulin family of plasma proteins and its name is derived from the ability to precipitate a group C polysaccharide of pneumococcus in the presence of Ca2+. Serum levels of CRP are elevated in a wide variety of acute and chronic inflammatory conditions. These conditions include most bacterial and some viral infections, rheumatic fever, rheumatoid arthritis, and many collagen diseases. CRP serum levels are also valuable in detection and evaluation of tissue injury, acute myocardial infarction, transplant rejection, and several malignant disorders. |