RAF

LUT014 View larger

LUT014

AT15794

CAS 2274819-46-2

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$51.00

$51.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.95 Total: $2,295.00
150 $26.52 Total: $1,326.00
125 $31.11 Total: $777.75
110 $36.72 Total: $367.20
15 $43.35 Total: $216.75

Data sheet

Molecular FormulaC27H19F3N8O
Molecular Weight528.49
CAS Numbers2274819-46-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc2c(Nc3cccc(OC(F)(F)F)c3)nccc2c1Nc1ncccc1-c1ncnc2[nH]cnc12
ReferencesNoa Shelach. Novel braf inhibitors and use there of for treatment of cutaneous reactions. WO2019026065A2.

More info

LUT014, a B-Raf inhibitor (IC50: 11.7 nM), is developed to reduce dose-limiting acneiform lesions associated with EGFR inhibitors treatment.