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View larger Belvarafenib
AT5634
CAS 1446113-23-0
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.90 | Total: $144.50 |
| 1 | 10 | $24.48 | Total: $244.80 |
| 1 | 25 | $20.74 | Total: $518.50 |
| 1 | 50 | $17.68 | Total: $884.00 |
| 1 | 100 | $15.30 | Total: $1,530.00 |
Data sheet
| Molecular Formula | C23H16ClFN6OS |
| Molecular Weight | 478.93 |
| CAS Numbers | 1446113-23-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12 |
| References | Son J B , Jung S H , Choi Ii W , et al. Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases[J]. 2015. |
More info
Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.