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Fosfructose, sodium salt, hydrate (1:3:8) View larger

Fosfructose, sodium salt, hydrate (1:3:8)

AT37984

CAS 81028-91-3

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Data sheet

Molecular FormulaC6H27Na3O20P2
Molecular Weight550.18
CAS Numbers81028-91-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
Synonym
IUPAC/Chemical Name
InChl Key
InChl Code
SMILES CodeC([C@H]([C@H]([C@@H](C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]
ReferencesWang DS, et al. Establishment and evaluation of a rabbit model of arterial thrombosis by collagen encapsulated thread-drawing. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008;33[11] 993-998.

More info

D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction mediated by fructose-1, 6-diphosphatase-1 is one of the rate-limiting steps of gluconeogenesis. The same reaction occurs in the chloroplasts of plants, D-Fructose-1,6-bisphosphate sodium salt hydrate as part of the reducing pentose phosphate cycle. Since cancer cells use glycolysis as a primary source of metabolic energy production, this pathway has become a major target for cancer chemotherapy.