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View larger Carglumic Acid
AT0755
CAS 1188-38-1
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Data sheet
| Molecular Formula | C6H10N2O5 |
| Molecular Weight | 190.15 |
| CAS Numbers | 1188-38-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [C@@H](CCC(O)=O)(NC(N)=O)C(O)=O |
| References | Carglumic acid. Prescrire Int. 2008 Apr;17[94] 50-1. |
More info
Carglumic Acid (Ureidoglutaric acid) is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence. This rare hereditary disease results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and lead to neurologic problems, coma, cerebral edema, and death. Carglumic acid was approved by the U.S. FDA on 18 March 2010.