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Malonic acid View larger

Malonic acid

AT5291

CAS 141-82-2

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$82.00

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Data sheet

Molecular FormulaC3H4O4
Molecular Weight104.06
CAS Numbers141-82-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)CC(O)=O
ReferencesOhdoi C, et al. Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 15;792[1] 123-30.

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Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism.