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Ethaselen View larger

Ethaselen

AT39664

CAS 217798-39-5

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$85.00

$85.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $38.25 Total: $3,825.00
150 $44.20 Total: $2,210.00
125 $51.85 Total: $1,296.25
110 $61.20 Total: $612.00
15 $72.25 Total: $361.25

Data sheet

Molecular FormulaC16H12N2O2Se2
Molecular Weight422.2
CAS Numbers217798-39-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C=2C=CC=CC2[Se]N1CCN3[Se]C=4C=CC=CC4C3=O
ReferencesLihui Wang, et al. Ethaselen a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent. Free Radic Biol Med. 2012 Mar 1;52[5] 898-908.

More info

Ethaselen (BBSKE) is an orally active and selective thioredoxin reductase 1 (TrxR) inhibitor with anticancer activity that directly inhibits TrxR1 activity and is commonly used in combination with oxaliplatin to inhibit tumor growth.Ethaselen induces apoptosis in cancer cells and inhibits the proliferation of colorectal cancer cells.