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> Rare Chemicals>?-(difluoromethyl)-DL-Arginine

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?-(difluoromethyl)-DL-Arginine View larger

?-(difluoromethyl)-DL-Arginine

AT35449

CAS 69955-43-7

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$62.00

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $52.70 Total: $263.50
110 $44.64 Total: $446.40
125 $37.82 Total: $945.50
150 $32.24 Total: $1,612.00
1100 $27.90 Total: $2,790.00

Data sheet

Molecular FormulaC7H14F2N4O2
Molecular Weight224.21
CAS Numbers69955-43-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(CCCNC(=N)N)(C(F)F)(C(O)=O)N
ReferencesGill, S.S., et al. Polyamines and abiotic stress tolerance in plants. Plant Signal. Behav. 5[1], 26-33 [2010].

More info

?-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 ?M), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, ?-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models.