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E235 View larger

E235

AT78077

CAS 891894-69-2

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$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.55 Total: $2,655.00
150 $30.68 Total: $1,534.00
125 $35.99 Total: $899.75
110 $42.48 Total: $424.80
15 $50.15 Total: $250.75

Data sheet

Molecular FormulaC28H25FN4OS
Molecular Weight484.59
CAS Numbers891894-69-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(NC1CCN(CC=2C=CC=CC2)CC1)C3=CC=C4C(SC5=NC(=CN54)C=6C=CC(F)=CC6)=C3
ReferencesSayers CM, et al. Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response. Mol Pharmacol. 2013 Mar;83[3] 594-604.

More info

E235 is a regulatory activator of transcription factor 4 (ATF4) with antiproliferative activity.E235 acts by initiating the integrated stress response (ISR) and signaling the DNA damage response.