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View larger Tetrahydroxystilbene-2-O-?-D-glucoside
AT4956
CAS 55327-45-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $49.30 | Total: $246.50 |
| 1 | 10 | $41.76 | Total: $417.60 |
| 1 | 25 | $35.38 | Total: $884.50 |
| 1 | 50 | $30.16 | Total: $1,508.00 |
| 1 | 100 | $26.10 | Total: $2,610.00 |
Data sheet
| Molecular Formula | C20H22O9 |
| Molecular Weight | 406.38 |
| CAS Numbers | 55327-45-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C1=C(C=CC2=CC=C(O)C=C2)C=C(O)C=C1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O |
| References | Activating mitochondrial function and haemoglobin expression with EH?201, an inducer of erythropoietin in neuronal cells, reverses memory impairment[J]. British Journal of Pharmacology, 2015, 172[19] 4741-4756. |
More info
Tetrahydroxystilbene-2-O-?-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-?-D-glucoside induces expression of erythropoietin, PPAR-? coactivator 1? (PGC-1?) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-?-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, A? and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-?-D-glucoside in their diet, levels of erythropoietin, PGC-1? and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-?-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.