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Tetrahydroxystilbene-2-O-?-D-glucoside View larger

Tetrahydroxystilbene-2-O-?-D-glucoside

AT4956

CAS 55327-45-2

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$58.00

$58.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.10 Total: $2,610.00
150 $30.16 Total: $1,508.00
125 $35.38 Total: $884.50
110 $41.76 Total: $417.60
15 $49.30 Total: $246.50

Data sheet

Molecular FormulaC20H22O9
Molecular Weight406.38
CAS Numbers55327-45-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO(C1=C(C=CC2=CC=C(O)C=C2)C=C(O)C=C1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
ReferencesActivating mitochondrial function and haemoglobin expression with EH?201, an inducer of erythropoietin in neuronal cells, reverses memory impairment[J]. British Journal of Pharmacology, 2015, 172[19] 4741-4756.

More info

Tetrahydroxystilbene-2-O-?-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-?-D-glucoside induces expression of erythropoietin, PPAR-? coactivator 1? (PGC-1?) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-?-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, A? and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-?-D-glucoside in their diet, levels of erythropoietin, PGC-1? and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-?-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.