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N-Formyl-Met-Leu-Phe-Lys View larger

N-Formyl-Met-Leu-Phe-Lys

ATP1168

CAS 67247-11-4

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$113.00

$113.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $50.85 Total: $5,085.00
150 $58.76 Total: $2,938.00
125 $68.93 Total: $1,723.25
110 $81.36 Total: $813.60
15 $96.05 Total: $480.25

Data sheet

Molecular FormulaC27H43N5O6S
Molecular Weight565.73
CAS Numbers67247-11-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O
ReferencesHe HQ, et al. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands. J Biol Chem. 2014 Jan 24;289[4] 2295-306.

More info

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 ?M for FPR2, and 0.88 ?M for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.