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Gue1654

AT27502

CAS 397290-30-1

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$63.00

$63.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $28.35 Total: $2,835.00
150 $32.76 Total: $1,638.00
125 $38.43 Total: $960.75
110 $45.36 Total: $453.60
15 $53.55 Total: $267.75

Data sheet

Molecular FormulaC23H17N3OS3
Molecular Weight447.6
CAS Numbers397290-30-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5
ReferencesCossette C, Gravel S, Reddy CN, Gore V, Chourey S, Ye Q, Snyder NW, Mesaros CA, Blair IA, Lavoie JP, Reinero CR, Rokach J, Powell WS. Biosynthesis and actions of 5-oxoeicosatetraenoic acid [5-oxo-ETE] on feline granulocytes. Biochem Pharmacol. 2015 Aug 1;96[3] 247-55. doi 10.1016j.bcp.2015.05.009. PubMed PMID 26032638; PubMed Central PMCID PMC4830392.

More info

Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygenglucose deprivation-induced injury in mice through activation of BCAT1.Gue1654 inhibits OXE-R-inhibited protein kinase C-? (PKC-?)nuclear factor ?B (NF-?B) signaling and apoptosis in cardiomyocytes. Gue1654 can be used to study cardiovascular disease.