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trans-isrib A17 View larger

trans-isrib A17

AT67783

CAS 1628478-15-8

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$51.00

$51.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.95 Total: $2,295.00
150 $26.52 Total: $1,326.00
125 $31.11 Total: $777.75
110 $36.72 Total: $367.20
15 $43.35 Total: $216.75

Data sheet

Molecular FormulaC22H22Cl2F2N2O4
Molecular Weight487.32
CAS Numbers1628478-15-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO(CC(N[C@H]1CC[C@H](NC(COC2=CC(F)=C(Cl)C=C2)=O)CC1)=O)C3=CC(F)=C(Cl)C=C3
ReferencesHearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11[8] 870-80.

More info

trans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.