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(Rac)-MGV354 View larger

(Rac)-MGV354

AT12670

CAS 1852495-86-3

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$60.00

$60.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $27.00 Total: $2,700.00
150 $31.20 Total: $1,560.00
125 $36.60 Total: $915.00
110 $43.20 Total: $432.00
15 $51.00 Total: $255.00

Data sheet

Molecular FormulaC35H37N5O3
Molecular Weight575.7
CAS Numbers1852495-86-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Nc3ccc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12)C(O)=O
ReferencesEhara T, et al. The Discovery of [ S]-1-[6-[3-[[4-[1-[Cyclopropanecarbonyl]piperidin-4-yl]-2-methylphenyl]amino]-2,3-dihydro-1 H-inden-4-yl]pyridin-2-yl]-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma. J Med Chem. 2018 Mar 22;61[6] 2552-2570.

More info

(Rac)-MGV354 (MGV354) is the racemate of MGV354. MGV354 is a soluble activator of guanylate cyclase (sGC)(EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively).