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Olorofim

AT27300

CAS 1928707-56-5

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$332.00

$332.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $149.40 Total: $14,940.00
150 $172.64 Total: $8,632.00
125 $202.52 Total: $5,063.00
110 $239.04 Total: $2,390.40
15 $282.20 Total: $1,411.00

Data sheet

Molecular FormulaC28H27FN6O2
Molecular Weight498.55
CAS Numbers1928707-56-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C(NC1=CC=C(C=C1)N2CCN(CC2)C=3N=CC(F)=CN3)=O)(=O)C4=C(C=C(C)N4C)C5=CC=CC=C5
ReferencesMirbzadeh Ardakani E, et al. Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo. Antimicrob Agents Chemother. 2021;65[12] e0138621.

More info

Olorofim is a novel selective antifungal compound with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM) and almost no inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against various pathogenic filamentous and dimorphic fungi such as Penicillium spp, Dermatophilus spp and Fusarium spp.