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View larger PDD00017272
AT39356
CAS 1945950-20-8
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $71.40 | Total: $357.00 |
| 1 | 10 | $60.48 | Total: $604.80 |
| 1 | 25 | $51.24 | Total: $1,281.00 |
| 1 | 50 | $43.68 | Total: $2,184.00 |
| 1 | 100 | $37.80 | Total: $3,780.00 |
Data sheet
| Molecular Formula | C23H25N5O4S3 |
| Molecular Weight | 531.67 |
| CAS Numbers | 1945950-20-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ncc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)s1 |
| References | Bohdan Waszkowycz, et al. Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly[ADP-ribose] Glycohydrolase [PARG] Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J Med Chem. 2018 Dec 13;61[23] 10767-10792. |
More info
PDD00017272 (34f) is a potent inhibitor of poly(ADP-ribose) glycohydrolase (PARG), exhibiting an EC50 value of 4.8 nM in biochemical assays and 9.2 nM in cellular POM.