Rare Chemicals

Nemorubicin View larger

Nemorubicin

AT4469

CAS 108852-90-0

More details

Molarity Calculation Cart®

HOW TO ORDER

$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC32H37NO13
Molecular Weight643.64
CAS Numbers108852-90-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4cccc(OC)c4C(=O)c3c(O)c12)C(=O)CO)O[C@H]1C[C@@H]([C@H](O)[C@H](C)O1)N1CCO[C@@H](C1)OC
ReferencesQuintieri L, et al. In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs a comparison with human liver microsomes. Biochem Pharmacol. 2008 Sep 15;76[6] 784-95.

More info

Nemorubicin (PNU 152243) is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives.