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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $286.45 | Total: $1,432.25 |
| 1 | 10 | $242.64 | Total: $2,426.40 |
| 1 | 25 | $205.57 | Total: $5,139.25 |
| 1 | 50 | $175.24 | Total: $8,762.00 |
| 1 | 100 | $151.65 | Total: $15,165.00 |
Data sheet
| Molecular Formula | C15H15N5 |
| Molecular Weight | 265.31 |
| CAS Numbers | 223788-33-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1C=2C(N=C1NN=C(C)C3=CC=CC=N3)=CC=CC2 |
| References | Rohira AD, et al. Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells. Cancer Res. 2017 Aug 15;77[16] 4293-4304. |
More info
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.